Nutrition Issues
Bernadette Festa, RD, MS; Pat Kearney, RD and Ernest H Rosenbaum, MD

Nutrition
Loss of Appetite
Nausea and Vomiting
Diarrhea
Constipation

When Foods Taste or Smell Funny
Chewing or Swallowing Difficulties
Weight Gain
Summary
Herbs and Supplements


Nutrition
Bernadette Festa, MS,RD; Pat Kearney RD; Ernest Rosenbaum, MD
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Good nutrition is needed for general good health and is particularly important when you are ill. During this time, it is important to give your body the proteins, fats, carbohydrates, vitamins and minerals it needs for energy, repair of normal tissue, and to keep your immune system strong to fight disease. Food is not only something to delight the taste but is an essential ingredient in the fight against disease. It is as important as your medicine or medical therapy (e.g., surgery, radiotherapy, or chemotherapy). Because of your illness or treatments, you may not be able to eat in the same way as before. You might find that your pleasurable experiences around eating are affected.

During illness, you will be more attuned to the smell, taste and texture of foods. As your senses will be acute, it is important to savor and enjoy foods now more than ever. However, you may find that your tastes have changed and you are turned off by foods that you once enjoyed (food aversions). Allow your memory of the enjoyment to encourage you to seek these foods as well as to develop a taste for new foods.

Think of yourself as an explorer. Sample small portions of foods previously eaten, try new tastes and note the reaction your body and spirit have to them. Even an explorer needs a map to chart unknown territory. With the help of a registered dietitian you can learn to explore alternative tastes and foods. Classes and counseling sessions have been set up at Stanford and we are in the process of setting these up at the Mt. Zion campus of UCSF. Dietitians Bernadette Festa, MS, RD, and Patricia Kearny, RD can address your personalized needs. The goal of our class and counseling is to provide current information which will help you maintain or improve your nutritional status and help you better fight your illness.

You may have no, one, or more symptoms from therapy. Everyone is different and there is no set pattern. The bright side is that most cancer survivors do not have these problems for very long after therapy has been completed, and some may not have any eating problems at all.

Loss of Appetite - A Common Problem
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You may not be able to rely on your hunger mechanism as a signal to eat. Many problems as pain, nausea, vomiting and diarrhea or a sore or dry mouth may make eating difficult and cause you to loss interest in eating. Depression, stress and anxiety also cause a loss of appetite. As appetite may no longer motivate you, now you need a planned approach.

Nausea and Vomiting
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Nausea is a frequent side effect of cancer treatment or the cancer itself.

Diarrhea
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Diarrhea may be due to many causes. You may get it because of chemotherapy, radiation therapy to the lower abdomen, malabsorption or sometimes antibiotics can cause diarrhea. It can also develop because of an intolerance to milk or difficulty in absorbing fats. Whatever the cause, diarrhea can be uncomfortable and embarrassing and causes you to lose vitamins, minerals and water.

Constipation
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Constipation may be caused by some chemotherapy medications as Vincristine, Vinblastine. Other drugs as morphine and codeine may contribute.

What you can do

When Foods Taste or Smell Funny
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You may notice a metallic or bitter taste in your mouth or that foods just don't taste as good. This can occur during certain cancer treatments, especially during or after chemotherapy or if you have received radiation therapy to the neck and mouth area.

When foods taste too bitter

When foods taste ``off''

Generally

Eating in relaxed and pleasant surroundings may help reduce problems with Taste blindness. -Flavorings such as herbs, spices or food seasonings may help. Acidic foods such as grapefruit may stimulate taste buds (but avoid them if they irritate your mouth).

Chewing or Swallowing Difficulties
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Soreness and tenderness in the mouth and throat are not uncommon. If your swallowing difficulties are minor the following suggestions may help. You May need to work with a swallowing therapist or consider alternative methods of feeding if you have severe problems.

Weight Gain
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Gaining weight may be due to chemotherapy, prescribed steroids as prednisone, or fluid retention. Steroids may change your metabolism or the way your body uses calories and may also increase your appetite.

While you are being treated for cancer this is not the time to go on a strict weight loss program as your body requires nourishment.

Summary
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Remember -

-The times when you are weak and do not feel like eating are the times when you need the energy, protein and protective factors from foods most.

DO

Herbs and Supplements
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We are always asked questions regarding the use of herbs and supplements. Keep in mind that herbs are not regulated in the US. There are no standards so formulations vary in potency and recommended dosages. Always seek a diagnosis from a physician before taking herbs, especially for serious conditions and inform your medical team of herbs you are taking so a crosscheck can be made for contraindications of use with other prescription medications.

Some of the most common questions for supplements are on selenium, garlic, carotenoids and isoflavones.

Selenium - Researchers currently advise against supplements until they can prove anti-cancer benefits as well as decide on the amount to optimize health without toxicity. It is believed that an amount of 200 micrograms a day is probably safe. Some food superstars are brazil nuts (4), 436 micrograms (mcg), 3.5 ounces of light tuna -50 mcg., 3.5 oz. Pork sirloin - 52 mcg., 1 cup cooked pasta - 30 mcg. IF you are taking supplemental selenium and are undergoing radiation, be sure to speak with your dietitian or medical team about possible interactions.

Garlic: growing research suggests garlic and its allium cousins are effective cancer fighters but the American Cancer Society for one is hesitant to endorse garlic, citing too little evidence as yet. Garlic supplements can lower blood sugar so this is not recommended for diabetics on medications. People with a clotting disorder or on blood thinners need to check with their physician before using supplements. Most nutritionists will recommend using both raw and cooked garlic in your diet instead of supplements.

Carotenoids: research results have been mixed and there are possible risks of single carotenoid supplementation. Consumption of foods rather than supplements, particularly vegetables and fruits that contain other protective substances is preferred, eating at least 5 to 9 servings per day. Lycopene, another powerful carotenoid antioxidant has been listed in recent ketchup ads as a cancer prevention food. Be aware that label comparisons are shown per ounce not per serving. One study found a daily consumption of 40 milligrams (mgs) did boost blood levels of carotenoids. Some rich food sources include - cup of tomato sauce - 23 mgs., 6 oz. Vegetable juice- 18 mgs., 8 oz. Tomato soup - 12 mgs.,

2 tablespoons ketchup - 6 mgs and 1 medium tomato 4 mg.

Isoflavones: These phytoestrogens are found in soy foods. Benefits are thought to be increased by as little as one serving of soy food per day. Eating soy foods is still preferable to using supplements and as a protein source and can replace animal saturated fat. Some rich food sources are l cup soy milk - 70mgs,1 oz. soy nuts - 40 mgs, 1/2 cup of tofu - 40 mgs, 1/2 cup of cooked soybeans - 35 mgs. Recent research suggests that if you have estrogen positive or hormone positive breast cancer that you should avoid taking in large amounts of soy products.Generally a few servings per week are acceptable.

Most of the questions we receive on herbs are on the following four: ginger, bilberry, milk thistle and saw palmetto. Here is a brief pro and con review.

Ginger ( zingifer officials)- May be useful for nausea and indigestion and may work by promoting secretion of saliva and digestive juices, neutralizing stomach acid and toxins, increasing tone and movement in intestines. There are capsules available or try 2 cups of tea using l teaspoon (tsp) fresh ginger or 1 1/2 tsp. powdered ginger. Excessive amounts may cause heartburn. Do not use for postoperative nausea as it may prolong bleeding or with combinations of other blood thinners.

Bilberry: (vaccinium Myrtillus) may be useful for simple diarrhea. There are capsules however it may be easier to make a tea using 1 tablespoon (tbl) of dried berries per cup. Do not use the leaves and fresh berries as they may have a laxative effect. Bilberry may prolong blood coagulation so caution is advised if taking other blood-thinning agents, like aspirin.

Milk thistle: (silybum Marianum) May be useful for chronic inflammatory diseases of the liver such as cirrhosis or hepatitis. Liver conditions require a physician's care. Milk thistle may work by acting on cell membranes to prevent toxins from entering the liver. Acts as an antioxidant. If you take: use seed extracts standardized to at least 70% silymarin at daily dose of 200 to 400 mgs. Teas are not effective because silymarin is not water soluble. It may have a mild laxative effect and is a possible allergen for those sensitive to ragweed.

Saw Palmetto (serenoa repens) may be useful for early non-cancerous prostate enlargement. May lessen symptoms but does not reduce prostate size. May work by counteracting androgenic hormones and fighting inflammation. If you take it: the usual dose is 320 mgs.dried fruit extract in 1 to 2 doses. Teas are of little value because few of the active ingredients are water soluble. Large amounts may cause diarrhea. Prostate enlargement requires physician care and there is some concern that the herb may cause inaccurate readings on prostate-specific antigen (PSA) tests.

For additional information refer to:

l.Tyler's Herbs of Choice or Tyler's Honest Herbal, Haworth herbal Press #l-800-Haworth

2. Consumer Reports on Health, March l999, pp. 8-9

3. Berkeley Wellness Letter

4. Dietary Supplements, August l998

5. Beyond Vitamins, the New Nutrition Revolution, April l999


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From Supportive Cancer Care
by Ernest H. Rosenbaum, MD & Isadora R. Rosenbaum, MA
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